Immunity, genes and therapy for Type 1 Diabetes
- Name
- Prof Mark Peakman
- Address
- Department of Immunobiology, King's College
London School of Medicine
2nd Floor, Borough Wing,
Guy's Hospital, London - Postcode
- SE1 9RT
- Telephone
- 44‐207‐188‐0148
- [email protected]
- Host Institution
- King's College London
The “Immunity, genes and therapy for Type 1 Diabetes” Research Network Writing Group includes academic physicians, clinician scientists, scientists and clinical consultants with interests in adult or paediatric diabetes, clinical immunology, medical genetics and intervention and prevention trials in Type 1 diabetes. The major research questions this group aims to address are (i) the nature of the aetiopathogenesis of Type 1 diabetes; (ii) the role of genetic elements in conferring risk; (iii) the contribution of different arms of the immune system to β‐cell death/survival and how these are genemodified; leading to (iv) the rational development and optimization of strategies for intervention and prevention of the disease. Our research activities span wet‐laboratory discovery research in immunology and genetics, through studies on human subjects to decipher disease biomarkers and understand pathogenesis, leading to translational activities in the clinical trial arena. Our overarching goal is to establish a cohort of UK investigators committed to making basic science observations a platform for the development or optimization of immune‐based therapies for Type 1 diabetes.
Membership
- Mark Peakman - Professor of Clinical Immunology, King’s College London and Honorary Consultant Immunologist, King’s College Hospital
- Timothy Barrett - Professor of Paediatrics/ Honorary Consultant in Paediatric Endocrinology and Diabetes, University of Birmingham
- Polly Bingley - Professor of Diabetes, University of Bristol
- Colin Dayan - Head of Clinical Research, University of Bristol (from Sept 2010, Professor of Clinical Diabetes and Metabolism, Cardiff University)
- David Dunger - Professor of Paediatrics, University of Cambridge and Honorary Consultant Paediatrician, Addenbrooke’s Hospital, Cambridge
- Nicky Leech - Consultant in Diabetes and Metabolic Medicine, Newcastle upon Tyne Hospitals Trust and Honorary Senior Lecturer, University of Newcastle
- David Leslie - Professor of Diabetes and Autoimmunity, Barts and The London School of Medicine and Dentistry, Queen Mary, London.
- Parth Narendran - Senior Lecturer and Honorary Consultant, University of Birmingham and University Hospital Birmingham NHS Foundation Trust
- James Shaw - Professor of Regenerative Medicine for Diabetes and Honorary Consultant Physician, Institute of Cellular Medicine, Newcastle University
- John Todd - Professor of Medical Genetics, University of Cambridge
- Timothy Tree - Senior Lecturer in Immunobiology, King’s College London
- Linda Wicker - Professor of Immunogenetics, University of Cambridge
- Susan Wong - Professor of Immunology, University of Bristol and Honorary Consultant Physician in Endocrinology and Diabetes, United Bristol NHS Healthcare Trust