Detection and prevention of diabetic complications in children and adolescents with Type I diabetes
- Name
- Professor David Brian Dunger
- Address
- University of Cambridge
Department of Paediatrics
Box 116 Level 8 Addenbrooke’s NHS Trust
Hills Road, Cambridge - Postcode
- CB2 0QQ
- Telephone
- 01223 336 886
- [email protected]
- Host Institution
- University of Cambridge
The research group will focus on the detection and prevention of diabetic complications in children and adolescents with type 1 diabetes. The group will work with three established cohorts of children with TID; the Oxford Regional Prospective Study of Childhood Diabetes (ORPS n500), Nephropathy Family Study (NFS n1,000), the JDRF/ Wellcome Trust Genetic Resource Investigating Diabetes (GRID n8,000).
The principal aims of the group will be to identify biomarkers (albumin excretion, measures of glomerular filtration, lipids and lipoproteins, carotid artery intima medial thickness, associated familial phenotypes) and common genetic variation which relates to risk for complications. These markers will form the basis for intervention studies, principally exploring the use of ACE inhibitors and statins to determine their role in providing cardiorenal protection during adolescence.
Membership
- Professor David Dunger – Professor of Paediatrics
- Dr Carlo Acerini – Clinical Lecturer, Paediatrics
- Dr Rakesh Amin – Consultant, Paediatric Endocrinology
- Professor Tim Barrett – Professor of Paediatric Endocr
- Dr Jackie Buck – Consultant Paediatrician
- Dr Tim Cheetham – Senior Lecturer, Paediatric Endocrinology
- Dr Neil Dalton – Senior Lecturer, Paediatric Biochemistry
- Professor John Deanfield – Professor of Cardiology
- Dr Julie Edge – Consultant Paediatrics/Diabetes & Endocrinology
- Professor Andrew Neil – Professor of Clinical Epidemiology
- Dr Toby Prevost – Medical Statistician
- Dr Julian Hamilton Shield – Reader, Diabetes & Metabolic Endocrinology
- Dr Nandu Thalange – Consultant Paediatrics/Paediatric Endocrinologist
- Professor John Todd – Professor Medical Genetics, Director Diabetes & Inflammation Laboratory
- Dr Nicholas Wareham – Director, MRC Epidemiology Unit (Medical Research Council)